Best counter-picks
These heroes are listed as strong answers into D.Va.
Tank
ZaryaZarya's primary fire pierces through D.Va's Defense Matrix. Zarya can easily gain barrier charge by using her barrier during D.Va's Micro Missiles
Junker QueenJunker Queen's Carnage pierces through D.Va's Defense Matrix
RoadhogRoadhog's Hook pierces through D.Va's Defense Matrix
Damage
MeiMei's Endothermic Blaster is a beam, so it cannot be blocked by D.Va's Defense Matrix. Even if D.Va closes in, Mei can buy time with Cryo-Freeze
SymmetraD.Va's Defense Matrix cannot block beams. Since D.Va often dives, Turret is also effective
ShionSupport
BrigitteBrigitte's primary attacks and abilities are not absorbed by D.Va's Defense Matrix
MizukiMizuki can negate D.Va's dive with Mizuki:E or dodge it with Mizuki:Shift
Favorable targets
D.Va is listed as performing well into these heroes.
Tank
No standout picks are listed.
Damage
WidowmakerWidowmaker has great difficulty dealing with Booster engagements
AsheHer attacks are easily absorbed by D.Va's Defense Matrix. Even if Ashe uses Coach Gun against Booster engagements, Boosters has a very short cooldown, so D.Va can close the gap again
HanzoHis attacks are easily absorbed by D.Va's Defense Matrix. Hanzo has difficulty dealing with Booster engagements
Support
AnaHer attacks are easily absorbed by D.Va's Defense Matrix. Ana has great difficulty dealing with Booster engagements
ZenyattaHis attacks are easily absorbed by D.Va's Defense Matrix. Zenyatta has great difficulty dealing with Booster engagements
MercyD.Va can commit to airborne targets