Best counter-picks
These heroes are listed as strong answers into Doomfist.
Tank
OrisaOrisa can cancel Doomfist during his Power Block or while charging Rocket Punch with Javelin. She can also negate the knockback from Rocket Punch by using Fortify
RoadhogRoadhog can easily land Hook on Doomfist during Power Block, while charging Rocket Punch, or right after Meteor Strike
MaugaDoomfist has no barrier, making him vulnerable to Mauga's burning effect
Damage
EchoDoomfist has difficulty committing to airborne targets
PharahDoomfist has difficulty committing to airborne targets
CassidyCassidy can cancel Doomfist's abilities or create a big opening by landing Flashbang on him
Support
AnaAna can easily land Sleep or Biotic Grenade on Doomfist during Power Block, while charging Rocket Punch, or right after Meteor Strike
BrigitteBrigitte can use Whip Shot to create distance from Doomfist or displace his Rocket Punch. With good timing, she can counter Rocket Punch with her bash
MoiraMoira can easily dodge Doomfist's Rocket Punch or Meteor Strike with Fade
Favorable targets
Doomfist is listed as performing well into these heroes.
Tank
No standout picks are listed.
Damage
BastionBastion is an easy target for Doomfist's Rocket Punch and Hand Cannon
WidowmakerWidowmaker has great difficulty dealing with Doomfist engages
Support
ZenyattaZenyatta is an easy target for Doomfist's Rocket Punch and Hand Cannon